Fullerene (C60) immunoconjugates: interaction of water-soluble C60 derivatives with the murine anti-gp240 melanoma antibody

Chem Commun (Camb). 2006 Jul 28:(28):3004-6. doi: 10.1039/b601717g. Epub 2006 Jun 9.

Abstract

The first fullerene (C60) immunoconjugates have been prepared and characterized as an initial step toward the development of fullerene immunotherapy (FIT).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / metabolism*
  • Antibodies, Neoplasm / metabolism*
  • Fullerenes / chemistry
  • Fullerenes / immunology
  • Fullerenes / metabolism*
  • Immunoconjugates / immunology
  • Immunoconjugates / metabolism*
  • Magnetic Resonance Spectroscopy
  • Melanoma / immunology
  • Mice
  • Proteoglycans / immunology*

Substances

  • Antibodies, Monoclonal
  • Antibodies, Neoplasm
  • Fullerenes
  • Immunoconjugates
  • Proteoglycans
  • gp240 glycoprotein, human
  • fullerene C60