Abstract
A new molecular subtyping approach was developed which is based on the amplification and sequencing of a repetitive region of the P1 gene of Mycoplasma pneumoniae. It allows the differentiation of all known subtypes and variants of M. pneumoniae as well as the identification of new subtypes directly in clinical samples to characterize endemic and epidemic M. pneumoniae infections.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adhesins, Bacterial / classification
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Adhesins, Bacterial / genetics
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Amino Acid Sequence
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Bacterial Typing Techniques*
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DNA, Bacterial / classification
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DNA, Bacterial / genetics
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Humans
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Molecular Epidemiology / methods*
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Molecular Sequence Data
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Mycoplasma pneumoniae / classification*
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Mycoplasma pneumoniae / genetics
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Mycoplasma pneumoniae / isolation & purification
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Pneumonia, Mycoplasma / epidemiology
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Pneumonia, Mycoplasma / microbiology*
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Polymerase Chain Reaction / methods
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Sequence Analysis, DNA
Substances
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Adhesins, Bacterial
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DNA, Bacterial
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adhesin, Mycoplasma pneumoniae