Determination of gamma-glutamyl conjugates of monoamines by means of high-performance liquid chromatography with electrochemical detection and application to gastropod tissues

J Chromatogr. 1991 Jun 14;567(1):49-56. doi: 10.1016/0378-4347(91)80308-y.

Abstract

Catabolism of aminergic neurotransmitters in gastropods appears to be primarily by means of gamma-glutamyl conjugation rather than by oxidative deamination as is typical of vertebrates. High-performance liquid chromatography with electrochemical detection was used to develop a method for the routine measurement of gamma-glutamyl conjugates of dopamine and 5-hydroxytryptamine in gastropod tissues.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biogenic Monoamines / analysis*
  • Biogenic Monoamines / metabolism
  • Chromatography, High Pressure Liquid
  • Electrochemistry
  • Glutamates / metabolism*
  • Glutamic Acid
  • Hydrogen-Ion Concentration
  • Oxidation-Reduction
  • Snails / metabolism*

Substances

  • Biogenic Monoamines
  • Glutamates
  • Glutamic Acid