Chemo-differentiating MCRs based on alpha-ketoesters and terminal alkynoates. A homoaldol-based ABB' system

David Tejedor; Alicia Santos-Expósito; Fernando García-Tellado

doi:10.1039/b605075a

Chemo-differentiating MCRs based on alpha-ketoesters and terminal alkynoates. A homoaldol-based ABB' system

Chem Commun (Camb). 2006 Jul 5:(25):2667-9. doi: 10.1039/b605075a. Epub 2006 May 18.

Authors

David Tejedor¹, Alicia Santos-Expósito, Fernando García-Tellado

Affiliation

¹ Instituto de Productos Naturales y Agrobiología, CSIC, Astrofísico Francisco Sánchez 3, 38206 La Laguna, Tenerife, Canary Islands, Spain.

PMID: 16786081
DOI: 10.1039/b605075a

Abstract

A novel ABB' 3 component reaction (3-CR) system based on the organocatalyzed homoaldolic condensation of alpha-ketoesters in the presence of terminal conjugated alkynoates is described.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry*
Alkynes / chemistry*
Catalysis
Esters / chemistry*
Ethylamines / chemistry
Ketones / chemistry*
Methylation
Molecular Structure
Propionates / chemistry

Substances

Aldehydes
Alkynes
Esters
Ethylamines
Ketones
Propionates
3-hydroxybutanal
propiolic acid
triethylamine