Analysis of results related to good and bad outcomes of Intacs implantation for keratoconus correction

J Cataract Refract Surg. 2006 May;32(5):756-61. doi: 10.1016/j.jcrs.2006.02.012.

Abstract

Purpose: To evaluate factors influencing good and poor outcomes after intracorneal ring segment implantation to correct keratoconus.

Setting: Instituto Oftalmológico de Alicante (Vissum Corporation), University of Miguel Hernandez, Alicante, Spain.

Methods: A retrospective comparative study of the visual outcome, 25 eyes of 21 patients were implanted after intracorneal ring segments (Intacs, Addition Technology) as a method to correct keratoconus. Outcomes were evaluated 6 months after implantation based on the visual results. Group A comprised 20 eyes that gained 3 lines or more of best spectacle-corrected visual acuity (BSCVA) to correct keratoconus, and Group B comprised 5 eyes that lost 1 line of BSCVA.

Results: In Group A, the preoperative mean BSCVA was 0.43 (20/50) and the postoperative mean BSCVA, 0.82 (20/20) (P< or =.0001). In Group B, the preoperative mean BSCVA was 0.36 (20/63) and the postoperative mean BSCVA, 0.24 (20/80) (P< or =.02). The preoperative mean sphere power was 3.90 diopters (D) greater in Group B than in Group A (P< or =.007); the mean spherical equivalent was 4.36 D greater (P< or =.007), and the mean K-reading was 6.91 D greater (P< or =.001). The postoperative reduction in spherical dioptric power was 2.11 D (P< or =.027) and the mean spherical equivalent, 2.81 D (P< or =.003), significant only in Group A. The reduction in mean central K-readings was 4.30 D (P< or =.0001) in Group A and 6.19 D (P< or =.014) in Group B. The correlation of the preoperative mean K value to the postoperative BSCVA was significant at the .01 level by the Pearson test (-0.67). In Group A, all eyes (100%) had a mean K-reading < or =53 D. In Group B, 4 eyes (80%) had a mean K-reading > or =55 D.

Conclusion: Intacs provided better results in visual acuity and corneal topography quality and significantly reduced the spherical equivalent in eyes with keratoconus with relatively low mean K values (< or =53 D) and a relatively low spherical equivalent. In advanced keratoconus (mean K-reading > or =55 D), poor results can be anticipated.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Corneal Stroma / physiopathology
  • Corneal Stroma / surgery*
  • Corneal Topography
  • Female
  • Humans
  • Keratoconus / physiopathology
  • Keratoconus / surgery*
  • Male
  • Middle Aged
  • Prognosis
  • Prostheses and Implants*
  • Prosthesis Implantation / methods*
  • Retrospective Studies
  • Visual Acuity / physiology