The influence of clenbuterol on growth in rats

Comp Biochem Physiol A Comp Physiol. 1991;99(1-2):241-4. doi: 10.1016/0300-9629(91)90266-f.

Abstract

1. The influence was studied of a beta 2-agonist, clenbuterol, on mean gain of body weight, feed efficiency and growth of muscle tissue in female Wistar rats of three different weights (70, 150 and 200 g). 2. Clenbuterol significantly increases mean gain of body weight and feed efficiency in all the studies realised, but much more effectively in animals of greater age/weight (200 g). 3. In addition, it favours protein deposition in muscle, given that it increases significantly (P less than 0.001) the muscle/body weight ratio in all of the experiments.

MeSH terms

  • Animal Nutritional Physiological Phenomena
  • Animals
  • Clenbuterol / pharmacology*
  • Female
  • Growth / drug effects*
  • Growth / physiology
  • Muscle Proteins / metabolism
  • Muscles / anatomy & histology
  • Muscles / drug effects
  • Muscles / metabolism
  • Rats
  • Rats, Inbred Strains
  • Weight Gain / drug effects

Substances

  • Muscle Proteins
  • Clenbuterol