[Tuberculosis in HIV infected children]

Przegl Epidemiol. 2006;60(1):65-70.
[Article in Polish]

Abstract

Tuberculosis (TB) is important threat in HIV-infected people. Although there is slow but constant decline TB-infections among adults and children in Poland, about 30% HIV-(+) adults is coinfected with TB. There were 12 cases of TB in HIV(+) children diagnosed in Department of Pediatric Infectious Diseases in 1994-2005. The aim was analysis of reasons for TB diagnostic tests in HIV (+) children, coinfection HIV and TB and efficacy of anti TB treatment. TB diagnostics was performed in 23 children because of clinical indications (15/23) and conversion or excessive skin tests (8/23). There were bacteriological and radiological exams done in all cases of TB suspicion. When active TB was diagnosed there were 4 tuberculostatic drugs used (6-12 months). In latent or unlocalized TB-INH was used for 12 months.

Results: 12 cases of TB infection were diagnosed: active TB--4, BCG-itis--1, latent--1 and unlocalized TB--6. In 10 cases TB infection was excluded. All cases of tuberculostatic treatment was successful. 5/12 cases are presently treated.

Conclusions: Skin test is lonely, generally used method of TB control in HIV (+) children without clinical manifestations of TB. There is a necessity of diagnosis and chemoprophylaxis in all cases of conversion or enlarged (above 10 mm, vesicularis) skin test. TB diagnosis is an indication for HIV diagnostics.

Publication types

  • English Abstract

MeSH terms

  • AIDS-Related Opportunistic Infections / diagnosis*
  • AIDS-Related Opportunistic Infections / drug therapy
  • Adolescent
  • Anti-HIV Agents / therapeutic use
  • Antitubercular Agents / therapeutic use
  • Child
  • Female
  • HIV Seropositivity / diagnosis
  • HIV Seropositivity / drug therapy
  • Humans
  • Male
  • Mycobacterium tuberculosis / isolation & purification*
  • Poland
  • Tuberculin Test
  • Tuberculosis / diagnosis*
  • Tuberculosis / drug therapy

Substances

  • Anti-HIV Agents
  • Antitubercular Agents