Biochemistry of the para-sulfonato-calix[n]arenes

Chem Commun (Camb). 2006 Jun 21:(23):2425-38. doi: 10.1039/b600720c. Epub 2006 Mar 10.

Abstract

The biochemistry of the para-sulfonato-calix[n]arenes has shown rapid development during the past ten years, the highly diverse biomedical applications of these molecules now include anti-viral, anti-thrombotic activities, enzyme blocking and protein complexation. The future is even more promising as para-sulfonato-calix[n]arenes have, now, been shown to have potential in the diagnosis of prion-based diseases. Their innocuous nature, as far as is known at present, may open up their future use in medications.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acetylcholine / chemistry
  • Amino Acids / chemistry
  • Anti-Infective Agents* / chemical synthesis
  • Anti-Infective Agents* / chemistry
  • Anti-Infective Agents* / pharmacology
  • Calixarenes* / chemical synthesis
  • Calixarenes* / chemistry
  • Calixarenes* / pharmacology
  • Models, Molecular
  • Molecular Structure
  • Peptides / chemistry
  • Proteins / chemistry
  • Proteins / drug effects
  • Steroids / chemistry
  • Structure-Activity Relationship

Substances

  • Amino Acids
  • Anti-Infective Agents
  • Peptides
  • Proteins
  • Steroids
  • Calixarenes
  • Acetylcholine