Highly selective C-H functionalization/halogenation of acetanilide

J Am Chem Soc. 2006 Jun 14;128(23):7416-7. doi: 10.1021/ja060232j.

Abstract

Highly regioselective C-H functionalization/halogenation of acetanilides to produce ortho-haloacetanilides was catalyzed by Pd(OAc)2 and Cu(OAc) 2 with CuX2 as the halogen source.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetanilides / chemistry*
  • Carbon / chemistry*
  • Catalysis
  • Cobalt / chemistry
  • Halogens / chemistry*
  • Hydrogen / chemistry*
  • Ligands
  • Molecular Structure
  • Phosphines / chemistry
  • Styrene / chemistry
  • Vinyl Compounds / chemistry

Substances

  • Acetanilides
  • Halogens
  • Ligands
  • Phosphines
  • Vinyl Compounds
  • Cobalt
  • Styrene
  • Carbon
  • Hydrogen
  • phosphine