Liposarcoma is the second most common soft tissue sarcoma in adults after fibrosarcoma. Extremities and retroperitoneum are the most common sites. Intraabdominal and particulary mesocolic liposarcoma is a rare localisation. We report the case of a 64-year-old woman with a localized grade 1 liposarcoma of the right mesocolon treated by an extended right hemicolectomy. No further treatment was done because of the low grading and the disease-free margins. The patient is without any evidence of recurrence after one year.