Pimarane diterpene and cytochalasin derivatives from the endophytic fungus Eutypella scoparia PSU-D44

J Nat Prod. 2006 May;69(5):856-8. doi: 10.1021/np0600649.

Abstract

Two pimarane diterpenes, named scopararanes A (1) and B (2), and two cytochalasins, named scoparasins A (3) and B (4), along with 4,8-dihydroxy-6-methoxy-4,5-dimethyl-3-methyleneisochroman-1-one (5) and diaportheins A (6) and B (7) were isolated from a culture broth of the endophytic fungus Eutypella scoparia PSU-D44. Their antimicrobial activities against Staphylococcus aureus ATCC 25923 and Microsporum gypseum SH-MU-4 were examined.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abietanes* / chemistry
  • Abietanes* / isolation & purification
  • Abietanes* / pharmacology
  • Anti-Infective Agents* / chemistry
  • Anti-Infective Agents* / isolation & purification
  • Anti-Infective Agents* / pharmacology
  • Ascomycota / chemistry*
  • Cytochalasins* / chemistry
  • Cytochalasins* / isolation & purification
  • Cytochalasins* / pharmacology
  • Garcinia
  • Microbial Sensitivity Tests
  • Microsporum / drug effects*
  • Molecular Structure
  • Plant Leaves
  • Staphylococcus aureus / drug effects*
  • Thailand

Substances

  • Abietanes
  • Anti-Infective Agents
  • Cytochalasins