Gamma-pyranone derivatives and other constituents from Erigeron annuus

Pharmazie. 2006 May;61(5):474-7.

Abstract

Two new gamma-pyranone derivatives and a new triterpene, together with eight known compounds, were isolated from the aerial parts of Erigeron annuus. Their structures were elucidated by spectroscopic methods. Besides, the anti-tumor activities of the gamma-pyranone derivatives to human hepatoma (SMMC-7721), human embryo liver (L-02) and human leukemia (HL-60) cells were evaluated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Asteraceae / chemistry*
  • Camptothecin / analogs & derivatives
  • Camptothecin / pharmacology
  • Carcinoma, Hepatocellular / drug therapy
  • Cell Line, Tumor
  • Erigeron / chemistry*
  • Flavanones / chemistry
  • Flavanones / pharmacology*
  • HL-60 Cells
  • Humans
  • Magnetic Resonance Spectroscopy
  • Pyrones / chemistry
  • Pyrones / pharmacology*
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Phytogenic
  • Flavanones
  • Pyrones
  • 10-hydroxycamptothecin
  • Camptothecin