Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases

Angew Chem Int Ed Engl. 2006 Jun 2;45(23):3772-5. doi: 10.1002/anie.200600757.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aminopeptidases / antagonists & inhibitors*
  • Animals
  • Cattle
  • Cell Proliferation / drug effects
  • Endothelial Cells / drug effects
  • Glycoproteins / antagonists & inhibitors*
  • HeLa Cells
  • Humans
  • Inhibitory Concentration 50
  • Methionyl Aminopeptidases
  • Pyrimidines / pharmacology*

Substances

  • Glycoproteins
  • Pyrimidines
  • Aminopeptidases
  • METAP1 protein, human
  • METAP2 protein, human
  • Methionyl Aminopeptidases
  • pyrimidine