Practicalities of drugging the phosphatidylinositol-3-kinase/Akt cell survival signaling pathway

Clin Cancer Res. 2006 May 15;12(10):2964-6. doi: 10.1158/1078-0432.CCR-06-0617.
No abstract available

MeSH terms

  • Cell Survival*
  • Enzyme Inhibitors / pharmacology
  • Humans
  • Neoplasms / drug therapy
  • Neoplasms / enzymology
  • Neoplasms / physiopathology
  • Phosphatidylinositol 3-Kinases / metabolism*
  • Phosphoinositide-3 Kinase Inhibitors*
  • Proto-Oncogene Proteins c-akt / antagonists & inhibitors*
  • Proto-Oncogene Proteins c-akt / metabolism*
  • Signal Transduction

Substances

  • Enzyme Inhibitors
  • Phosphoinositide-3 Kinase Inhibitors
  • Proto-Oncogene Proteins c-akt