The levels of immunoglobulins of: M, A, G classes in 65 patients (11 women and 54 men) ill from epidemic parotitis, at acute phase and after subsidence of symptoms, were determined. The results of examinations were considered in two categories. One of them concerned all the patients, the other one comprised the patients with three groups of complications: meningitis, orchitis and joint occurrence of meningitis and orchitis. No deviations from the norm were found in IgM and IgA levels, both in acute phase and during convalescence. An increase of IgG content was observed only in the initial phase of epidemic parotitis. Taking into consideration the complications during the disease there was obtained an increase of IgM level in the patients with joint occurrence of meningitis and orchitis only in acute phase. Increased IgG values in the course of mumps concerned the patients with meningitis and orchitis and could be still observed after subsidence of the symptoms of the disease.