Abstract
We outline in this review how Borrelia burgdorferi, the causative agent of Lyme disease, moves from the tick to the vertebrate host, and what molecules are potentially involved in this challenging commute. The survival strategies utilized by the spirochete during transmission and the initial stages of infection are discussed.
MeSH terms
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Animals
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Arachnid Vectors / microbiology
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Borrelia burgdorferi / genetics
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Borrelia burgdorferi / pathogenicity*
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Borrelia burgdorferi / physiology
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Gene Expression Regulation, Bacterial
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Humans
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Ixodes / microbiology*
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Lyme Disease / immunology
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Lyme Disease / microbiology*
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Lyme Disease / transmission*