The protease inhibitor Ucf-101 induces cellular responses independently of its known target, HtrA2/Omi

Cell Death Differ. 2006 Dec;13(12):2157-9. doi: 10.1038/sj.cdd.4401955. Epub 2006 May 12.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activating Transcription Factor 3 / genetics
  • Activating Transcription Factor 3 / metabolism
  • Animals
  • Gene Expression Regulation / drug effects*
  • Gene Expression Regulation / physiology
  • High-Temperature Requirement A Serine Peptidase 2
  • Mice
  • Mice, Knockout
  • Mitochondrial Proteins / genetics
  • Mitochondrial Proteins / metabolism*
  • Pyrimidinones / pharmacology*
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Serine Endopeptidases / genetics
  • Serine Endopeptidases / metabolism*
  • Thiones / pharmacology*
  • Transcription Factor CHOP / genetics
  • Transcription Factor CHOP / metabolism

Substances

  • Activating Transcription Factor 3
  • Atf3 protein, mouse
  • Mitochondrial Proteins
  • Pyrimidinones
  • RNA, Messenger
  • Thiones
  • UCF 101
  • Transcription Factor CHOP
  • Serine Endopeptidases
  • High-Temperature Requirement A Serine Peptidase 2
  • Htra2 protein, mouse