Evaluation of health risks caused by radio frequency accelerated carcinogenesis: the importance of processes driven by the calcium ion signal

Eur J Cancer Prev. 2006 Jun;15(3):191-5. doi: 10.1097/01.cej.0000195711.56825.f8.

Abstract

The acceleration of carcinogenesis, which was induced either by radio frequency radiation from a cellular telephone or by the ferric-ATP complex, was similar in a mouse strain characterized by age-determined carcinogenesis of lymphoid tissues. Organ hypertrophy, the presence of lymphoid blood and ascites, the development of solid tumours, and mortality were very different to those found in control animals. These results emphasize the role of calcium ion signal influx in the activation of oncogenes and the failure of thymus-determined immune defences.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adenoma / etiology
  • Adenoma / pathology
  • Adenosine Triphosphate / pharmacology
  • Animals
  • Brain / drug effects
  • Brain / pathology
  • Calcium / physiology*
  • Calcium Channels / physiology
  • Carcinogenicity Tests / methods
  • Extremities / pathology
  • Female
  • Ferric Compounds / pharmacology
  • Kidney / drug effects
  • Kidney / pathology
  • Leiomyosarcoma / etiology
  • Leukemic Infiltration / etiology
  • Liver / drug effects
  • Liver / pathology
  • Lung / drug effects
  • Lung / pathology
  • Lung Neoplasms / etiology
  • Lung Neoplasms / pathology
  • Lymphoma / etiology
  • Mice
  • Models, Animal
  • Neoplasms / etiology*
  • Ovary / drug effects
  • Ovary / pathology
  • Radio Waves / adverse effects*
  • Risk Assessment
  • Signal Transduction / radiation effects
  • Spleen / drug effects
  • Spleen / pathology

Substances

  • Calcium Channels
  • Ferric Compounds
  • Adenosine Triphosphate
  • ferric-adenosine triphosphate complex
  • Calcium