Effect of CYP3A5*3 on carbamazepine pharmacokinetics in Japanese patients with epilepsy

Clin Pharmacol Ther. 2006 May;79(5):509-10. doi: 10.1016/j.clpt.2006.02.009.
No abstract available

Publication types

  • Comment
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anticonvulsants / pharmacokinetics*
  • Carbamazepine / pharmacokinetics*
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System / genetics*
  • Cytochrome P-450 Enzyme System / metabolism*
  • Epilepsy / drug therapy*
  • Female
  • Genotype
  • Humans
  • Japan
  • Male
  • Polymorphism, Genetic

Substances

  • Anticonvulsants
  • Carbamazepine
  • Cytochrome P-450 Enzyme System
  • CYP3A5 protein, human
  • Cytochrome P-450 CYP3A