Production of anti-tumor-promoting iridoid glucosides in Genipa americana and its cell cultures

J Nat Prod. 1991 Nov-Dec;54(6):1677-80. doi: 10.1021/np50078a032.

Abstract

The Genipa americana plant contains geniposide [3] and geniposidic acid [2] in the fruits and geniposidic acid [2] in the leaves. On callus induction, the plant produces tarennoside [1], geniposidic acid [2], and gardenoside [4] in high levels. The leaves of Ge. americana plants redifferentiated from the callus tissues produce 2.

MeSH terms

  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Glucosides / isolation & purification
  • Glucosides / pharmacology*
  • Herpesvirus 4, Human / drug effects
  • Humans
  • Iridoid Glucosides
  • Iridoids
  • Protein Kinase C / drug effects
  • Pyrans / isolation & purification
  • Pyrans / pharmacology*
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Phytogenic
  • Glucosides
  • Iridoid Glucosides
  • Iridoids
  • Pyrans
  • geniposide
  • geniposidic acid
  • Protein Kinase C
  • gardenoside