Basic ionic liquid as catalysis and reaction medium: a novel and green protocol for the Markovnikov addition of N-heterocycles to vinyl esters, using a task-specific ionic liquid, [bmIm]OH

Jian-Ming Xu; Bo-Kai Liu; Wei-Bo Wu; Chao Qian; Qi Wu; Xian-Fu Lin

doi:10.1021/jo0600914

Basic ionic liquid as catalysis and reaction medium: a novel and green protocol for the Markovnikov addition of N-heterocycles to vinyl esters, using a task-specific ionic liquid, [bmIm]OH

J Org Chem. 2006 May 12;71(10):3991-3. doi: 10.1021/jo0600914.

Authors

Jian-Ming Xu¹, Bo-Kai Liu, Wei-Bo Wu, Chao Qian, Qi Wu, Xian-Fu Lin

Affiliation

¹ Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China.

PMID: 16674082
DOI: 10.1021/jo0600914

Abstract

A basic ionic liquid, 1-methyl-3-butylimidazolium hydroxide ([bmIm]OH), has been introduced as a catalyst and reaction medium for the Markovnikov addition of N-heterocycles to vinyl esters under mild conditions. The evidence for the role of this basic ionic liquid [bmIm]OH in promoting the Markovnikov addition has been given. On the basis of the evidence, a mechanism was postulated.