Abstract
The effect of zosterin (pectin polysaccharide) on the protein-synthesizing function of mouse liver cells was studied after its intragastric administration of 1% gel zosterin. The drug modified the morphology and function of the nucleolar apparatus by changing the number and summary area of the nucleoli, content of Ag proteins, nucleolar/nuclear ratio, and increased protein content in hepatocyte cytoplasm.
MeSH terms
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Animals
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Cell Nucleolus / drug effects
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Cell Nucleus / chemistry
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Cell Nucleus / drug effects
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Cell Nucleus / genetics
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Cytoplasm / chemistry
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Cytoplasm / drug effects
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Hepatocytes / cytology
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Hepatocytes / drug effects*
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Hepatocytes / metabolism
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Liver / cytology
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Liver / drug effects*
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Liver / metabolism
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Male
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Mice
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Mice, Inbred Strains
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Ploidies
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Polysaccharides / pharmacology*
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Protein Biosynthesis / drug effects*
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Proteins / analysis
Substances
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Polysaccharides
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Proteins
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zosterin