Abstract
The in vivo expansion of suppressor/regulatory T cells (Tregs) is a desirable event in autoimmunity and transplantation. Here we summarize the general rules involved in antigen recognition by T cells and describe Tregs and their requirements, discussing different levels of immune intervention.
MeSH terms
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Antigens / immunology*
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Autoimmune Diseases / immunology*
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Autoimmunity*
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Dendritic Cells / immunology
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Humans
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Immune Tolerance
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Immunotherapy*
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Ligands
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Major Histocompatibility Complex / genetics
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T-Lymphocytes, Regulatory / immunology*
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T-Lymphocytes, Regulatory / transplantation
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Transplantation Tolerance / immunology