RIKEN structural genomics beamlines at the SPring-8; high throughput protein crystallography with automated beamline operation

Go Ueno; Hiroyuki Kanda; Raita Hirose; Koh Ida; Takashi Kumasaka; Masaki Yamamoto

doi:10.1007/s10969-005-9005-5

RIKEN structural genomics beamlines at the SPring-8; high throughput protein crystallography with automated beamline operation

J Struct Funct Genomics. 2006 Mar;7(1):15-22. doi: 10.1007/s10969-005-9005-5. Epub 2006 Apr 28.

Authors

Go Ueno¹, Hiroyuki Kanda, Raita Hirose, Koh Ida, Takashi Kumasaka, Masaki Yamamoto

Affiliation

¹ SPring-8/RIKEN, Kouto, Sayo-gun, Hyogo, 679-5148, Japan. ueno@spring8.or.jp

PMID: 16645781
DOI: 10.1007/s10969-005-9005-5

Abstract

RIKEN Structural Genomics Beamlines, BL26B1 & BL26B2 at the SPring-8, have been constructed for the structural genomics research. The main feature of the beamline is full automation of the successive data collections to maximize the beam-time efficiency. The beamline optics adopted a standard design commonly used for the SPring-8 bending magnet beamlines. Beamline instruments are operated by centralized control system through the computer network to achieve the automatic operation. The core part of the beamline development is a sample management system composed of sample changer robots for laboratory and beamline, and a networked sample database. BL26B1 has started user operation, and the automatic operation with the sample management system has been implemented at BL26B2.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Crystallography, X-Ray / instrumentation
Crystallography, X-Ray / methods
Databases, Factual
Genomics* / instrumentation
Genomics* / methods
Protein Conformation
Proteins / chemistry*
Robotics* / instrumentation
Robotics* / methods
User-Computer Interface*

Substances

Proteins