Allele frequencies for 15 STR loci in Tibetan populations from Nepal

Masao Ota; Yunden Droma; Buddha Basnyat; Yoshihiko Katsuyama; Hideki Asamura; Hironori Sakai; Hirofumi Fukuhsima

doi:10.1016/j.forsciint.2006.03.010

Allele frequencies for 15 STR loci in Tibetan populations from Nepal

Forensic Sci Int. 2007 Jul 4;169(2-3):234-8. doi: 10.1016/j.forsciint.2006.03.010. Epub 2006 Apr 18.

Authors

Masao Ota¹, Yunden Droma, Buddha Basnyat, Yoshihiko Katsuyama, Hideki Asamura, Hironori Sakai, Hirofumi Fukuhsima

Affiliation

¹ Department of Legal Medicine, Shinshu University School of Medicine, Asahi 3-1-1, 390-8621 Matsumoto, Japan. otamasao@sch.md.shinshu-u.ac.jp

PMID: 16621386
DOI: 10.1016/j.forsciint.2006.03.010

Abstract

Samples from 105 unrelated healthy Sherpa in Namche Bazaar and 111 unrelated non-Sherpa in Kathmandu valley from Nepal were used to obtain allele frequency data for 15 short tandem repeat (STR) loci (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPOX and vWA) included in the AmpFLSTR Identifiler kit. No deviations from Hardy-Weinberg equilibrium were observed, but only after applying a Bonferroni correction in the case of D5S818 in the Sherpa population and D7S820 in the Kathmandu population. Genetic parameters of forensic interest were calculated and genetic differentiation between the two populations tested.

MeSH terms

DNA Fingerprinting
Gene Frequency*
Genetics, Population*
Humans
Nepal
Polymerase Chain Reaction
Tandem Repeat Sequences*
Tibet