A simple and green procedure for the microbial effective synthesis of 1-phenylethyl alcohol in both enantiomeric forms

Małgorzata Brzezińska-Rodak; Ewa Zymańczyk-Duda; Magdalena Klimek-Ochab; Paweł Kafarski; Barbara Lejczak

doi:10.1007/s10529-006-0009-4

A simple and green procedure for the microbial effective synthesis of 1-phenylethyl alcohol in both enantiomeric forms

Biotechnol Lett. 2006 Apr;28(7):511-3. doi: 10.1007/s10529-006-0009-4.

Authors

Małgorzata Brzezińska-Rodak¹, Ewa Zymańczyk-Duda, Magdalena Klimek-Ochab, Paweł Kafarski, Barbara Lejczak

Affiliation

¹ Department of Bioorganic Chemistry, Wrocław University of Technology, 50-370 Wrocław, 27, Wybrzeze Wyspiańskiego, Poland. malgorzata.brzezinska-rodak@pwr.wroc.pl

PMID: 16614934
DOI: 10.1007/s10529-006-0009-4

Abstract

Both R- and S-phenylethyl alcohol of high enantiomeric purity (98%) and with a satisfactory yield (40-80%) were obtained by bioreduction of acetophenone, catalyzed by whole cells of baker's yeast.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acetophenones / metabolism*
Benzyl Alcohols / analysis
Benzyl Alcohols / chemistry*
Benzyl Alcohols / metabolism*
Cell Culture Techniques / methods*
Isomerism
Saccharomyces cerevisiae / metabolism*

Substances

Acetophenones
Benzyl Alcohols
methylphenyl carbinol
acetophenone