Urgent cardiac resynchronization therapy in patients with decompensated chronic heart failure receiving inotropic therapy. A case series

Cardiology. 2006;106(1):59-62. doi: 10.1159/000092616. Epub 2006 Apr 11.

Abstract

Background: It remains unknown whether patients with severe decompensated class IV heart failure (HF) receiving intravenous inotropic treatment benefit from cardiac resynchronization therapy (CRT).

Methods: We identified patients who underwent urgent CRT implantation due to decompensated class IV HF necessitating intravenous inotropic therapy.

Results: Of 10 patients with chronic ischemic cardiomyopathy (median QRS duration of 170 ms), CRT implantation was associated with symptomatic improvement in 8 patients. The mortality rate was 50% during a median follow-up of 9.5 months, with a median CRT-to-death duration of 6 months.

Conclusions: CRT was feasible among class IV patients receiving inotropic treatment and was associated with clinical improvement.

MeSH terms

  • Aged
  • Cardiac Pacing, Artificial*
  • Cardiotonic Agents / therapeutic use
  • Combined Modality Therapy
  • Defibrillators, Implantable*
  • Female
  • Heart Failure / mortality
  • Heart Failure / therapy*
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve Insufficiency / therapy
  • Retrospective Studies
  • Stroke Volume / physiology
  • Ventricular Dysfunction, Left / therapy*

Substances

  • Cardiotonic Agents