Technical refinement preserving segment 4 to donor in extended right hepatectomy

Hepatogastroenterology. 2006 Mar-Apr;53(68):253-7.

Abstract

Background/aims: Donor extended right hepatectomy, including the middle hepatic vein (MHV) and a part of segment 4 (Sg4), is performed to overcome inadequate graft for large adult recipient as resolving congestion of right anterior section. However, using this technique remnant donor liver is often too small. Here, we introduce a technical Modified extended right hepatectomy (MERH), in which the MHV was excavated preserving the entire Sg4 in the donor.

Methodology: We compared clinical outcomes between donors using our technique (n=12) that may result in Sg4 congestion, and right hepatectomy (RH, n=12) that may not. MERH was performed when the remnant donor liver had a volume exceeding 35% and showed no steatosis in preoperative imaging study.

Results: No donor died, and there were no differences in operative time and postoperative recovery between the two groups (p>0.05). The regeneration of the remnant liver after MERH and RH were similar (160.2% vs. 187.7% at POD 10; 222.2% vs. 230.5% at 4 months) (p>0.05).

Conclusions: Our results show that MERH didn't impair recovery or liver regeneration in donors, and indicate that MERH will be useful in adult living donor liver transplantation.

MeSH terms

  • Adult
  • Female
  • Hepatectomy / methods*
  • Humans
  • Liver / pathology*
  • Liver / physiopathology*
  • Liver Function Tests
  • Liver Regeneration / physiology*
  • Male
  • Middle Aged
  • Organ Size
  • Outcome Assessment, Health Care
  • Tissue and Organ Harvesting / methods*