Abstract
Centrifugal partition chromatography was applied to separate arctigenin and matairesinol from Forsythia koreana extract with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (5:5:5:5 v/v). Using this method, arctigenin and matairesinol were successfully separated from partially purified F. koreana extracts in only one step. The purities of isolated compounds were determined to be over 90% by HPLC analysis.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Chromatography, High Pressure Liquid / methods
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Countercurrent Distribution / methods*
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Forsythia / chemistry*
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Furans / analysis
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Furans / isolation & purification*
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Lignans / analysis
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Lignans / isolation & purification*
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Molecular Structure
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Plant Extracts / chemistry
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Solvents / chemistry
Substances
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Furans
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Lignans
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Plant Extracts
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Solvents
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matairesinol
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arctigenin