Abstract
Hepatitis E virus (HEV) is a major cause of hepatitis. We evaluated five HEV antibody diagnostic assays by using outbreak specimens. The Abbott immunoglobulin G (IgG), Genelabs IgG, and Walter Reed Army Institute of Research (WRAIR) IgM assays were about 90% sensitive; the Abbott IgG and WRAIR total Ig and IgM assays were more than 90% specific.
Publication types
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Evaluation Study
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Cross-Sectional Studies
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DNA, Viral / analysis
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Disease Outbreaks*
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Hepatitis Antibodies* / blood
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Hepatitis E / diagnosis*
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Hepatitis E / epidemiology*
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Hepatitis E / immunology
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Hepatitis E virus / genetics
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Hepatitis E virus / isolation & purification*
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Humans
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Immunoenzyme Techniques / methods
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Immunoenzyme Techniques / standards
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Retrospective Studies
Substances
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DNA, Viral
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Hepatitis Antibodies