Intermittent loading improves results in mandibular alveolar distraction osteogenesis

Clin Oral Implants Res. 2006 Apr;17(2):179-87. doi: 10.1111/j.1600-0501.2005.01213.x.

Abstract

Aim: To evaluate clinical and morphological effects on distractive callus after application of an original protocol of bone stimulation.

Material and methods: Traditional or mechanically stimulated alveolar-distraction osteogenesis was studied on 16 highly selected subjects subdivided into two groups. Clinical, radiological, densitometric and histological (on biopsies) analyses were performed 6, 8 and 12 weeks after distraction was completed.

Results: In subjects undergoing stimulated alveolar-distraction osteogenesis, bone density was higher and at histology, bone with ordered structure was observed after 6 weeks. Moreover, bone trabeculae with oriented architecture and greater amounts of lamellar bone were observed after 8 and 12 weeks in the same subjects.

Discussion and conclusions: In conclusion, although osteogenic processes were similar in both groups, they were induced earlier and were better structured in subjects undergoing stimulated alveolar-distraction osteogenesis. These encouraging results can only be achieved and preserved by strict monitoring of distractive vectors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon
  • Adolescent
  • Adult
  • Aged
  • Alveolar Bone Loss / surgery
  • Alveolar Process / pathology
  • Alveolar Process / ultrastructure
  • Alveoloplasty / methods*
  • Biopsy
  • Bone Density / physiology
  • Bone Regeneration / physiology
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mandible / pathology
  • Mandible / surgery*
  • Mandible / ultrastructure
  • Middle Aged
  • Osteogenesis / physiology
  • Osteogenesis, Distraction / methods*
  • Physical Stimulation
  • Stress, Mechanical