Gottron's papules-like eruption developing under hydroxyurea therapy

Rheumatol Int. 2006 Jun;26(8):768-70. doi: 10.1007/s00296-006-0123-6. Epub 2006 Apr 1.

Abstract

A 57-year-old white female developed a Gottron's papules (GP)-like eruption, without any of the other clinical or laboratory signs of dermatomyositis (DM). She was under hydroxyurea treatment for chronic myeloid leukemia at the time. Skin biopsy was compatible with seborrheic keratosis. Conditions presenting with GP but unrelated to DM are reviewed, with emphasis on hydroxyurea-induced skin lesions.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Coronary Angiography
  • Dermatologic Surgical Procedures
  • Dermatomyositis / complications
  • Dermatomyositis / diagnosis*
  • Dermatomyositis / pathology
  • Dermatomyositis / physiopathology
  • Dermatomyositis / surgery
  • Fatal Outcome
  • Female
  • Humans
  • Hydroxyurea / adverse effects*
  • Hydroxyurea / therapeutic use*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy*
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
  • Middle Aged
  • Skin / pathology

Substances

  • Hydroxyurea