An iterative route to "decorated" ethylene glycol-based linkers

Chem Commun (Camb). 2006 Apr 21:(15):1652-4. doi: 10.1039/b518061a. Epub 2006 Mar 7.

Abstract

Iterative copper-catalyzed cycloadditions of azides to alkynes were used to join functionalized triethylene glycol molecules to give "linkers" of defined lengths equipped with several different end-group functionalities.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Alkynes / chemistry
  • Azides / chemistry
  • Catalysis
  • Copper / chemistry
  • Cross-Linking Reagents / chemistry*
  • Ethylene Glycol / chemistry*

Substances

  • Alkynes
  • Azides
  • Cross-Linking Reagents
  • Copper
  • Ethylene Glycol