Microscopic hematuria as a predictive factor for detecting bladder cancer at cystoscopy in women with irritative voiding symptoms

Am J Obstet Gynecol. 2006 May;194(5):1423-6. doi: 10.1016/j.ajog.2006.01.053. Epub 2006 Mar 30.

Abstract

Objective: The purpose of this study was to assess microscopic hematuria as a predictive factor for detecting bladder cancer at cystoscopy in women with irritative voiding symptoms.

Study design: We conducted a retrospective cohort analysis of women with irritative voiding symptoms who presented for urodynamic testing and cystoscopy. Irritative voiding symptoms were defined as urgency, urge incontinence, frequency, dysuria, and/or nocturia. Patient demographics, risk factors for bladder cancer, presence of microscopic hematuria, urodynamic findings, and cystoscopy and biopsy results were recorded.

Results: Of 735 patients with irritative voiding symptoms, 264 (35.9%) had microscopic hematuria and 471 (64.1%) had no hematuria. Bladder cancer was detected in 3 women, for an overall detection rate of 0.4%. Microscopic hematuria, urgency, frequency, dysuria, nocturia, age, and tobacco use were not significantly associated with bladder cancer.

Conclusion: In this cohort of women with irritative voiding symptoms, microscopic hematuria was not predictive for bladder cancer.

MeSH terms

  • Aged
  • Cohort Studies
  • Cystoscopy*
  • Female
  • Hematuria / etiology*
  • Humans
  • Incidence
  • Middle Aged
  • Predictive Value of Tests
  • Retrospective Studies
  • Urinary Bladder Neoplasms / epidemiology
  • Urinary Bladder Neoplasms / pathology*
  • Urination Disorders / urine*