Unmet needs in the diagnosis and treatment of dyslipidemia in the primary care setting in Germany

Atherosclerosis. 2007 Feb;190(2):397-407. doi: 10.1016/j.atherosclerosis.2006.02.025. Epub 2006 Mar 20.

Abstract

Objectives and methods: DETECT is a cross-sectional study of 55,518 unselected consecutive patients in 3188 representative primary care offices in Germany. In a random subset of 7519 patients, an extensive standardized laboratory program was undertaken. The study investigated the prevalence of cardiovascular disease, known risk factors (such as diabetes, hypertension and dyslipidemia and their co-morbid manifestation), as well as treatment patterns. The present analysis of the DETECT laboratory dataset focused on the prevalence and treatment of dyslipidemia in primary medical care in Germany. Coronary artery disease (CAD), risk categories and LDL-C target achievement rates were determined in the subset of 6815 patients according to the National Cholesterol Education Program (NCEP) ATP III Guidelines.

Results: Of all patients, 54.3% had dyslipidemia. Only 54.4% of the NCEP-classified dyslipidemic patients were diagnosed as 'dyslipidemic' by their physicians. Only 27% of all dyslipidemic patients (and 40.7% of the recognized dyslipidemic patients) were treated with lipid-lowering medications, and 11.1% of all dyslipidemic patients (41.4% of the patients treated with lipid-lowering drugs) achieved their LDL-C treatment goals. In conclusion, 80.3% of patients in the sample with dyslipidemia went undiagnosed, un-treated or under-treated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Chemical Analysis
  • Blood Pressure
  • Coronary Disease / diagnosis
  • Coronary Disease / epidemiology
  • Coronary Disease / therapy
  • Cross-Sectional Studies
  • Diabetic Angiopathies / diagnosis
  • Diabetic Angiopathies / epidemiology
  • Diabetic Angiopathies / therapy
  • Dyslipidemias / diagnosis*
  • Dyslipidemias / epidemiology
  • Dyslipidemias / therapy
  • Germany / epidemiology
  • Humans
  • Primary Health Care / standards*