Treatment failure due to emergence of resistance to carbapenem during therapy for Shewanella algae bacteremia

J Clin Microbiol. 2006 Mar;44(3):1172-4. doi: 10.1128/JCM.44.3.1172-1174.2006.

Abstract

We describe a case of bacteremia due to imipenem-susceptible Shewanella algae. Despite treatment with imipenem, the patient developed a spinal epidural abscess, from which imipenem-resistant S. algae was isolated. The development of resistance should be monitored when S. algae infection is treated with imipenem, even though the strain is initially susceptible to imipenem.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bacteremia / drug therapy*
  • Bacteremia / microbiology*
  • Base Sequence
  • DNA Primers / genetics
  • DNA, Bacterial / genetics
  • DNA, Bacterial / isolation & purification
  • Drug Resistance, Bacterial
  • Gram-Negative Bacterial Infections / drug therapy*
  • Gram-Negative Bacterial Infections / microbiology*
  • Humans
  • Imipenem / therapeutic use*
  • Male
  • Polymerase Chain Reaction
  • Shewanella / drug effects*
  • Shewanella / genetics
  • Shewanella / isolation & purification
  • Treatment Failure

Substances

  • DNA Primers
  • DNA, Bacterial
  • Imipenem