Attacking pathogens through their hosts

Genome Biol. 2006;7(1):201. doi: 10.1186/gb-2006-7-1-201. Epub 2006 Jan 30.

Abstract

Through understanding the intricacies of host-pathogen interactions, it is now possible to inhibit the growth of microbes, especially viruses, by targeting host-cell proteins and functions. This new antimicrobial strategy has proved effective in the laboratory and in the clinic, and it has great potential for the future.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents / metabolism
  • Anti-Infective Agents / pharmacology*
  • Anti-Infective Agents / therapeutic use
  • Antiviral Agents / metabolism
  • Antiviral Agents / pharmacology*
  • Antiviral Agents / therapeutic use
  • HIV / drug effects
  • HIV / metabolism
  • HIV / pathogenicity*
  • Host-Parasite Interactions / drug effects*
  • Host-Parasite Interactions / physiology
  • Humans
  • Models, Biological

Substances

  • Anti-Infective Agents
  • Antiviral Agents