Laparoscopic excision of recurrent endometriomas: long-term outcome and comparison with primary surgery

Fertil Steril. 2006 Mar;85(3):694-9. doi: 10.1016/j.fertnstert.2005.08.028.

Abstract

Objective: To compare the laparoscopic excision of primary versus recurrent ovarian endometriomas.

Design: Descriptive study.

Setting: Tertiary referral center for the treatment of endometriosis.

Patient(s): Between 1993 and 2002, 359 consecutive patients: 305 primary surgeries (group A) and 54 reoperations for a recurrent endometrioma in the same ovary of the primary cyst (group B).

Intervention(s): Laparoscopic stripping of the cyst wall. Follow-up evaluations every 6 months, including clinical and ultrasonographic evaluations and a questionnaire for pain symptoms (mean follow-up time, +/- standard deviation: 35.4 +/- 27.6 months).

Main outcome measure(s): Recurrence of pain symptoms, sonographic recurrence of endometriomas, need for a new medical or surgical treatment, and reproductive outcome.

Result(s): In groups A and B, respectively, the 5-year cumulative rates were not statistically significantly different: pain recurrence 20.5% versus 17.4%; ultrasonographic recurrence 18.9% versus 15.1%; retreatment requirement 19.4% versus 17.3%; and pregnancy 40.8% versus 32.4%. Although the difference was not statistically significant, compared with patients of group A, the women of group B underwent assisted reproduction techniques more frequently (50% vs. 32.2%) and had more irregular menstrual cycles associated with follicle-stimulating hormone levels > or = 14 IU/mL in the early follicular phase (5.5% vs. 1.3%).

Conclusion(s): After laparoscopic excision of recurrent ovarian endometriomas, the recurrence of pain and the reproductive outcome are comparable with those found after primary surgery.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Endometriosis / physiopathology
  • Endometriosis / surgery*
  • Endometriosis / therapy
  • Female
  • Gynecologic Surgical Procedures*
  • Humans
  • Laparoscopy*
  • Longitudinal Studies
  • Ovarian Diseases / physiopathology
  • Ovarian Diseases / surgery*
  • Ovarian Diseases / therapy
  • Pain / physiopathology
  • Pregnancy
  • Pregnancy Rate
  • Recurrence
  • Retreatment
  • Survival Analysis
  • Treatment Outcome