Intravitreal triamcinolone acetonide for exudative age-related macular degeneration among Japanese patients

Ophthalmologica. 2006;220(2):118-24. doi: 10.1159/000090577.

Abstract

Aim: To study the results of intravitreal triamcinolone acetonide (TA) for exudative age-related macular degeneration (AMD) among Japanese patients.

Methods: 13 eyes of 12 Japanese patients (9 males and 3 females) with subfoveal choroidal neovascularization (CNV) of exudative AMD received intravitreal TA (8 mg). Visual acuity, size of CNV and serous retinal detachment, and complications related to treatment were evaluated for 6 months or longer.

Results: Postoperative maximum visual acuity significantly improved (p < 0.05). Postoperative eyes had a greater probability of a reduced size of CNV and/or retinal detachment compared to preoperative eyes. Seven eyes showed increased intraocular pressure (21 mm Hg or over), which was controlled well by medication. Cataract development and advancement were observed in 90% of phakic eyes. No other serious complications were found.

Conclusions: Intravitreal TA might be an effective treatment for subfoveal CNV of exudative AMD among Japanese as well as Caucasian patients for a comparatively short period.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Exudates and Transudates
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Fundus Oculi
  • Glucocorticoids / administration & dosage*
  • Humans
  • Injections
  • Intraocular Pressure
  • Macular Degeneration / drug therapy*
  • Macular Degeneration / epidemiology
  • Macular Degeneration / pathology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome
  • Triamcinolone Acetonide / administration & dosage*
  • Visual Acuity
  • Vitreous Body

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide