Antimicrobial and other properties of a new stabilized alkaline glutaraldehyde disinfectant/sterilizer

Am J Hosp Pharm. 1977 Apr;34(4):376-82.

Abstract

The properties of stabilized alkaline 2% glutaraldehyde solution (SGS) are discussed. SGS is discussed with regard to its chemistry, antimicrobial properties, organic soil resistance, toxicity, corrosivity and chemical stability. SGS retains the maximum antimicrobial activity of alkaline glutaraldehyde solutions and the chemical stability heretofore observed only with acidic glutaraldehyde solutions. These improvements, along with the inherent resistance of glutaraldehyde to neutralization by organic soil, allow SGS to be continuously used for 14 days in situations of high dilution, or 28 days in situations of low dilution.

MeSH terms

  • Administration, Oral
  • Administration, Topical
  • Aerosols
  • Aldehydes / pharmacology*
  • Animals
  • Anti-Bacterial Agents
  • Anti-Infective Agents*
  • Bacteria / drug effects
  • Chemical Phenomena
  • Chemistry
  • Corrosion
  • Disinfectants*
  • Drug Stability
  • Glutaral / administration & dosage
  • Glutaral / pharmacology*
  • Glutaral / toxicity
  • Hydrogen-Ion Concentration
  • Irritants
  • Lethal Dose 50
  • Microbial Sensitivity Tests
  • Rabbits
  • Rats
  • Soil Microbiology
  • Spores, Bacterial / drug effects
  • Time Factors
  • Viruses / drug effects

Substances

  • Aerosols
  • Aldehydes
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Disinfectants
  • Irritants
  • Glutaral