Abstract
The aim of this study was to determine the allele frequencies of genetic variants CCR5delta32, CCR2-64I, and SDF1-3'A (SDF1 801 A), which influence susceptibility to HIV-1 infection. We also investigated the effect of these variants on the general Ecuadoran population and on a group of HIV-infected individuals to determine the frequency of these genetics variants.
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Alleles
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Chemokine CXCL12
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Chemokines, CXC / genetics*
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Chi-Square Distribution
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Child
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Child, Preschool
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Ecuador
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Female
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Gene Frequency
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Genetic Predisposition to Disease
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Genetics, Population
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Genotype
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HIV Infections / genetics*
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HIV-1*
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Humans
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Infant
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Male
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Middle Aged
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Polymorphism, Genetic*
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Receptors, CCR2
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Receptors, CCR5 / genetics*
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Receptors, Chemokine / genetics*
Substances
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CCR2 protein, human
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CXCL12 protein, human
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Chemokine CXCL12
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Chemokines, CXC
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Receptors, CCR2
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Receptors, CCR5
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Receptors, Chemokine