Abstract
We report on the first detection of six copies of the capsulation b locus in a Haemophilus influenzae type b strain isolated from a splenectomized patient with fulminant septic shock associated with disseminated intravascular coagulation and death. The unusual amplification of the locus might have contributed to the rare and severe clinical presentation.
Publication types
-
Case Reports
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adult
-
Bacterial Capsules / genetics*
-
Disseminated Intravascular Coagulation / complications
-
Fatal Outcome
-
Female
-
Gene Dosage*
-
Genes, Bacterial
-
Haemophilus Infections / complications
-
Haemophilus Infections / microbiology*
-
Haemophilus Infections / surgery
-
Haemophilus influenzae type b / genetics
-
Haemophilus influenzae type b / isolation & purification*
-
Humans
-
Shock, Septic / microbiology*
-
Splenectomy*