Coronary artery bypass grafting within the first year after treatment of large acute myocardial infarctions with angioplasty or fibrinolysis

Scand Cardiovasc J. 2006 Feb;40(1):25-8. doi: 10.1080/14017430500243614.

Abstract

Objectives: To calculate the incidence and analyse and outcome after coronary artery bypass grafting (CABG) within the first year after randomisation of 1,572 patients with acute myocardial infarctions with ST-segment elevation (STEMI) to either percutaneous coronary intervention (PCI) or fibrinolysis.

Design: The study includes 131 patients: 108 male and 23 female with a mean age 62 years.

Results: The total 30-day mortality after CABG was 4.6% (7.5% in the PCI group and 2.6% in the fibrinolysis group). The 30-day mortality was 9.8% after CABG within the first 30-days and 1.3% after CABG within 31-365 days. The patients who were operated early had a reduced EF to 43% as compared to 50% in patients who were not operated or patients having CABG after 30-days (p=0.002).

Conclusion: CABG was performed within the first year after STEMI in 10% of patients randomised to fibrinolysis and in 6.7% of patients randomised to PCI. Patients having CABG within the first 30-days after treatment of STEMI had an increased mortality of 9.8%.

Publication types

  • Comparative Study

MeSH terms

  • Angioplasty, Balloon, Coronary*
  • Coronary Artery Bypass* / mortality
  • Coronary Artery Bypass* / statistics & numerical data
  • Coronary Restenosis / surgery*
  • Female
  • Fibrinolytic Agents / therapeutic use*
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / mortality
  • Myocardial Infarction / physiopathology
  • Myocardial Infarction / therapy*
  • Randomized Controlled Trials as Topic
  • Stroke Volume
  • Survival Analysis
  • Time Factors

Substances

  • Fibrinolytic Agents