Clinical and angiographic analysis with a cobalt alloy coronary stent (driver) in stable and unstable angina pectoris

Am J Cardiol. 2006 Feb 1;97(3):349-52. doi: 10.1016/j.amjcard.2005.08.051.

Abstract

The Clinical and Angiographic analysis with a Cobalt Alloy Coronary Stent (Driver) (CLASS) study was a prospective, nonrandomized, multicenter study designed to assess the safety and efficacy of a cobalt-chromium alloy-based stent in patients with stable or unstable angina pectoris. A total of 203 lesions were treated in 202 enrolled patients. The percentage of major adverse cardiac event-free patients was 87.6% (177 of 202) at 6 months (primary safety end point; major adverse cardiac events were defined as death, myocardial infarction, emergency bypass surgery, or target lesion revascularization [percutaneous transluminal coronary angioplasty or coronary artery bypass grafting]). The angiographic success rate (primary efficacy end point) was 100%, and the procedural success rate was 98%. The binary in-stent restenosis rate at 6 months was 12.6%. Our results have demonstrated that the Driver cobalt-chromium alloy stent can be used with a low 6-month incidence of major adverse cardiac events, a low 6-month binary restenosis rate, and high angiographic and procedural success rates.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Aged
  • Angina Pectoris / diagnostic imaging
  • Angina Pectoris / therapy*
  • Biocompatible Materials / therapeutic use*
  • Chromium Alloys / therapeutic use*
  • Coronary Angiography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Stents*
  • Treatment Outcome

Substances

  • Biocompatible Materials
  • Chromium Alloys