Abstract
[structure: see text]. A convergent and module-based strategy for the asymmetric synthesis of the western hemisphere (C1-C17 fragment) of salinomycin has been devised. This new synthetic approach relies on highly stereoselective C-glycosidation and aldol processes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aldehydes / chemistry
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Anti-Bacterial Agents / chemical synthesis*
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Anti-Bacterial Agents / chemistry
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Ionophores
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Molecular Structure
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Pyrans / chemical synthesis*
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Pyrans / chemistry
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Stereoisomerism
Substances
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Aldehydes
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Anti-Bacterial Agents
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Ionophores
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Pyrans
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salinomycin
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3-hydroxybutanal