Transverse myelitis in systemic lupus erythematosus: two cases with magnetic resonance imaging

Br J Rheumatol. 1992 Aug;31(8):555-8. doi: 10.1093/rheumatology/31.8.555.

Abstract

Transverse myelitis is one of the most serious neurological complications occurring in the course of systemic lupus erythematosus. We describe two lupus patients, with transverse myelitis, one of whom had associated optic neuritis. In both, magnetic resonance imaging of the spinal cord showed an abnormal signal. In one case a good response to steroid and immunosuppressive therapy was observed; the other case failed to improve despite the therapy applied.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Combined Modality Therapy
  • Cyclophosphamide / therapeutic use
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / therapy
  • Magnetic Resonance Imaging*
  • Male
  • Myelitis, Transverse / complications*
  • Myelitis, Transverse / diagnosis*
  • Myelitis, Transverse / therapy
  • Plasmapheresis
  • Spinal Cord / pathology
  • Steroids / therapeutic use
  • Whole-Body Irradiation

Substances

  • Adrenal Cortex Hormones
  • Immunosuppressive Agents
  • Steroids
  • Cyclophosphamide