The role of second autografts in the management of myeloma at first relapse

Haematologica. 2006 Jan;91(1):141-2.

Abstract

We report an analysis of the value of a second high-dose melphalan autograft, performed at relapse, on a series of newly diagnosed myeloma patients entered into the high-dose program at our center. We conclude that relapse-free survival after the first autograft is a major prognostic factor in determining outcome.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disease Management
  • Disease-Free Survival
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Melphalan / therapeutic use
  • Multiple Myeloma / mortality
  • Multiple Myeloma / therapy*
  • Prognosis
  • Recurrence
  • Salvage Therapy
  • Transplantation, Autologous

Substances

  • Melphalan