Abstract
Selenocysteine containing peptoids and peptide-peptoid conjugates were synthesized by combinatorial Ugi-MCRs (multicomponent reactions) in water: for the first time, an acetal (selenoacetal 2a) was used in Ugi-MCR to furnish selenocysteine peptoids in one step as model compounds for selenocysteine peptides and proteins.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Acetals / chemistry
-
Combinatorial Chemistry Techniques*
-
Heterocyclic Compounds / chemistry*
-
Models, Chemical
-
Peptide Library*
-
Peptoids / chemical synthesis*
-
Selenocysteine / chemical synthesis*
-
Water / chemistry*
Substances
-
Acetals
-
Heterocyclic Compounds
-
Peptide Library
-
Peptoids
-
Water
-
Selenocysteine