Is there life after Buckley's Formocresol? Part I -- a narrative review of alternative interventions and materials

Int J Paediatr Dent. 2006 Mar;16(2):117-27. doi: 10.1111/j.1365-263X.2006.00688.x.

Abstract

Objectives: (1) To present a narrative review of the currently available alternative interventions and materials to formocresol pulpotomy for the management of extensive caries in the primary molar, and (2) to produce a clinical protocol for pulp therapy techniques in the extensively carious primary molar.

Introduction: The International Agency for Research on Cancer has recently classified formaldehyde as carcinogenic to human beings. Since Buckley's Formocresol contains 19% formaldehyde in its full strength and, therefore, 1% in a 20% dilution, a safer alternative should be identified.

Methods: A narrative review of the published literature for primary molar pulp therapy techniques was undertaken following an extensive and appropriate literature search. A specialist group of paediatric dentists was formed to arrive at a consensus and establish an evidence-based protocol for the management of extensively carious primary molar teeth. Part I of this paper explores the currently available alternative interventions and materials to formocresol in the form of a narrative review. The second part of the paper will present the formation of a specialist group to arrive at a consensus and establish an evidence-based protocol for the management of the extensively carious primary molar.

Conclusions: After consideration of a review of extensively searched literature, a protocol and key points document have been developed to assist clinicians in their treatment planning. Further long-term studies with the highest level of evidence (i.e. randomized controlled trials) are required to enable us to identify acceptable alternatives which can replace formocresol.

Publication types

  • Review

MeSH terms

  • Aluminum Compounds / therapeutic use
  • Animals
  • Bone Morphogenetic Proteins / therapeutic use
  • Calcium Compounds / therapeutic use
  • Calcium Hydroxide / therapeutic use
  • Camphor / therapeutic use
  • Collagen / therapeutic use
  • Demeclocycline / therapeutic use
  • Dental Pulp Capping / methods
  • Dental Pulp Devitalization / methods
  • Dental Pulp Exposure / therapy*
  • Drug Combinations
  • Electrosurgery
  • Ferric Compounds / therapeutic use
  • Formocresols
  • Glutaral / therapeutic use
  • Humans
  • Hydrocarbons, Iodinated / therapeutic use
  • Laser Therapy
  • Oxides / therapeutic use
  • Pulpectomy / methods
  • Pulpotomy / methods*
  • Root Canal Filling Materials / therapeutic use
  • Silicates / therapeutic use
  • Silicones / therapeutic use
  • Tooth Remineralization / methods
  • Triamcinolone Acetonide / therapeutic use
  • Zinc Oxide-Eugenol Cement / therapeutic use

Substances

  • Aluminum Compounds
  • Bone Morphogenetic Proteins
  • Calcium Compounds
  • Drug Combinations
  • Ferric Compounds
  • Formocresols
  • Hydrocarbons, Iodinated
  • Oxides
  • Root Canal Filling Materials
  • Silicates
  • Silicones
  • Zinc Oxide-Eugenol Cement
  • calcium hydroxide, iodoform, silicone oil drug combination
  • mineral trioxide aggregate
  • Kri paste
  • formocresol
  • ferric sulfate
  • Demeclocycline
  • Camphor
  • Ledermix
  • Collagen
  • Triamcinolone Acetonide
  • Calcium Hydroxide
  • Glutaral