Assessment of acute spontaneous intracerebral hematoma by CT perfusion imaging

J Neuroradiol. 2005 Dec;32(5):333-6. doi: 10.1016/s0150-9861(05)83164-5.

Abstract

A single-section deconvolution-derived computerized tomographic perfusion imaging was performed in 45 patients (22 male and 23 female; mean age=69.89+/-10.07 years) with acute supratentorial spontaneous intracerebral hemorrhage. Mean rCBF and rCBV were lower in the hemorrhagic core than in the perihematomal low density area (p<0.001), and in the perihematomal low density area than in normal appearing brain parenchyma (p<0.001). Mean rMTT values were higher in perihematomal low density area than in normal appearing area (p<0.01) and in both hemorrhagic and perihematomal area than in controlateral ROI (p<0.001). There were no differences in rMTT mean values between hemorrhagic core and perihematomal area, as well as between normal appearing and controlateral areas. We found a concentric distribution of all CT perfusion parameters characterized by an improvement from the core to the periphery, with low perihematomal rCBF and rCBV values suggesting edema formation.

MeSH terms

  • Acute Disease
  • Aged
  • Cerebral Hemorrhage / diagnostic imaging*
  • Cerebral Hemorrhage / physiopathology*
  • Cerebrovascular Circulation / physiology*
  • Female
  • Hematoma / diagnostic imaging*
  • Hematoma / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Tomography, X-Ray Computed